Health & Environmental Research Online (HERO)

Print Feedback Export to File
Journal Article 
Antioxidant and anti-cancer activity of Chia seed extract in breast cancer cell line 
Mutar, HA; Alsadooni, JFK 
Wolters Kluwer Medknow Publications 
Cancer is one of the deadly disease which recorded highly incidence in last decades, cancer term refers to more than 100 types of malignant tumors have different etiological and pathological features, each of these has occupied a great deal of researches interestinglike using phytochemicals medicine. The aims of present study are one such effort exploring the beneficial role of Salvia hispanica seeds against the growth of breast cancer cells. Different extracts of Chia seeds (Salvia hispanica) were prepared, then tests were carried out for phytochemical analysis of the aqueous, alcoholic extracts also chloroform, petroleum ether and n-hexane solvent for plant extracts. Determination of the Free Radical and Antioxidant scavenging activities of the Chia seed (Salvia hispanica) was performed. Analysis of MTT Assay using Breast Cancer cell line (Mcf-7) methanolic extract show that it has many phytochemicals compound than others types of extracts also it has high percentage of free radical scavenger according to DPPH tests, the anticancer activity was carried out using methanolic extract, the results show that viability of cell line was decreased with elevation of plant extract concentrations. Therefore, this preliminary work adds on and ensures the enormous possibilities of research in this area to bring out effective drug against breast cancer for the benefit of humans. © Annals of Tropical Medicine & Public Health S241 
Cancer; Cytotoxicity; MTT assay