US EPA

8152491 

Journal Article 

Effect of 1-(4-chloro-phenylazo)-naphthalen-2-ol and 2-[1- (4-Chloro-phenylimino)-ethyl]-phenol with Cu(II), Ni(II), Zn(II), Co(II) and Mn(II) ions on bacterial growth 

Usharani, M; Akila, E; Rajavel, R 

2013 

5 

2 

311-319 

English 

A new Schiff base mixed ligand metal complexes were synthesized with the Schiff base derived from 2-hydroxyacetophenone and 4-Chloroaniline and 1-(4-chloro-phenylazo)-naphthalen-2-ol. The complexes were formulated as mononuclear species on the basis of chemical analysis, molar conductance, IR, Electrochemical, Magnetic studies, electronic spectral and ESR studies. The Schiff base and its metal complexes are soluble in common organic solvent but insoluble in water. The empirical formula calculation of the complex compounds indicated the formula [ML1L2] for Cu(II), Ni(II) & Zn(II) and [ML1L2X2] for Co(II) & Mn(II) Schiff base mixed ligand complexes. The conductivity data for all the complexes are consistent with those expected for non electrolyte. The infrared spectral data shows the coordination site that is via -OH, C=N and N=N groups of the mentioned ligands. The electronic and ESR spectra exhibit the expected geometrical structures for the prepared chelates. The 3D molecular modelling and analysis also gives the bond lengths and bond angles for the following representative complex [CuL1L2]. The free ligand and its metal complexes showed higher antibacterial effects than that of some investigated bacteria. 

Antibacterial activity; Mixed ligand complexes; Mononuclear Schiff base complexes; Octahedral and square planar geometry