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HERO ID
8158433
Reference Type
Journal Article
Title
Brief review on cyclopropane analogs: Synthesis and their pharmacological applications
Author(s)
Ajay Kumar, K
Year
2013
Is Peer Reviewed?
1
Journal
International Journal of Pharmacy and Pharmaceutical Sciences
ISSN:
2656-0097
EISSN:
0975-1491
Volume
5
Issue
1
Page Numbers
454-459
Language
English
Abstract
The unique reactivity of cyclopropanes due to the high level of strain offers considerable utility in organic synthesis. Many imaginative applications of cyclopropanes as useful building blocks have been predicated on regio-and stereo-controlled ring-opening reactions of substituted cyclopropanes. Cyclopropane analogs have known to exhibit diverse pharmacological applications that created enormous interest in Bioorganic, Medicinal and Pharmaceutical chemistry. This review article depicts the up to date information about the conventional to modified methods of synthesis of cyclopropane analogs and their biological activities. The structure activity relationship was also discussed.
Keywords
Anti HIV; Antimicobacterial; Antimicrobial; Antioxidant; Cyclopropane; Maleimides
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