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8163183 
Journal Article 
Improving the chemical status of peloids by adding the phytocomplex in the rehabilitation of patients with osteoarthritis: Experimental study 
Babaskina, LI; Litvinova, TM; Babaskin, DV; Winter, EA; Krylova, OV 
2018 
10 
5 
1238-1242 
English 
The use of peloids in combination with the phytocomplex necessitates studying the compatibility and balance of their chemical compositions, which will contribute to the efficiency of peloid therapy in patients with osteoarthritis. The goal is to study the chemical composition of the peloid and the phytocomplex for their integrated use for rehabilitation of patients with osteoarthritis. Materials and methods. Peat peloid and phytocomplex, which is a dry extract from marsh cinquefoil, alfalfa and common hop. The mineral composition was studied using the mass-spectral and atomic-emission methods; flavonoids were separated and identified by the methods of column thin-layer liquid chromatography with the use of standard samples; the spectrophotometric method was used for quantitative determination of flavonoids; the amino acid composition was determined with an amino acid analyzer. Results and discussion. It has been found that peloid and phytocomplex are rich in most important macro-and micronutrients that prevent lesion of the main components of the joint and, as a result, prevent emergence and development of osteoarthritis. The phytocomplex contained rather large amounts of flavonoids (7.08+0.17%) represented by flavonols and their glycosides, isoflavones, and one compound from the group of coumestans – cumestrole. The study of amino acid composition has shown that the content of some amino acids, which are the most important for preventing and treating osteoarthritis, in the complex exceeds that in peat peloid. Conclusion. Chemical compositions of the peloid and the phytocomplex are compatible and balanced, which makes it possible to assume that it will have a positive effect on the results of rehabilitation of osteoarthritis patients with their integrated use. © 2018, Pharmainfo Publications. All rights reserved. 
Amino acid composition; Biologically active substances; Flavonoids; Herbal medicine; Mineral elements; Peloid therapy