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8168705 
Journal Article 
De behandeling van malaria 
Kager, PA; Zijlmans, CWR; Boele Van Hensbroek, M; Wetsteyn, J 
1997 
1 
Nederlands Tijdschrift voor Geneeskunde
ISSN: 0028-2162
EISSN: 1876-8784 
141 
37 
1774-1778 
Dutch 
The diagnosis of malaria should include the species involved and in case of P. falciparum infection the parasitaemia index: the percentage of the infected red cells. P. vivax, ovale and malariae infection are treated with chloroquine, in case of P. vivax and ovale malaria followed by primaquine. Mefloquine and halofantrine are indicated for chloroquine-resistant vivax infections. Advice on management and treatment is different for mild and severe (≤ 5% infected erythrocytes or presence of complications) P. falciparum infections. Mild infections may be treated on an outpatient basis. In severe infections quinine has to be started immediately, while frequent checks of vital functions and blood parameters are indicated. New treatment options are the use of artemisinine (preparations) or atovaquon, both efficacious and low in adverse effects and toxicity.