Strawberry is a widely grown hybrid species of the genus Fragaria (Rubiaceae family). It is cultivated worldwide for its fruit, which is an aggregate accessory fruit widely appreciated for its characteristic aroma, bright red color, juicy texture, and flavor. The world strawberry production reached 4,516,810 tons in 2012, being the USA, Mexico, Turkey, Spain, Egypt, Russia, South Korea, Japan, Poland and Germany the main producers. Strawberry is one of the most sensitive plants in horticultural production and nutrient management is a key factor to ensure high yields and fruit quality. Furthermore, an adequate management of nutrient elements is crucial to guarantee health food safety and food quality. As well, soil health plays a pivotal role in insect and disease management as well as in providing a foundation for building soil fertility. In this chapter we present the most important and recent advances on nutrient management of strawberry, in relation to macronutrients (nitrogen, phosphorus, potassium, sulfur, calcium and magnesium) and micronutrients (iron, boron, manganese, zinc, copper, molybdenum and nickel) that play a crucial role on production, quality, as well as pest and disease control. Moreover, we explore the potential use of some beneficial elements, as they may stimulate growth, can compensate toxic effects of other elements, or increase tolerance to biotic stress. © 2014 by Nova Science Publishers, Inc. All rights reserved.