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8184102 
Meetings & Symposia 
SYNTHESIS OF THE DIHYDRODIOL AND DIOL EPOXIDE METABOLITES OF CARCINOGENIC POLYCYCLIC HYDROCARBONS 
Harvey, RG 
1985 
Yes 
ACS Symposium Series
ISSN: 0097-6156
EISSN: 1947-5918 
ACS 
Washington, DC, USA 
Polycyclic Hydrocarbons and Carcinogenesis. Developed from a symposium held at the 188th Meeting of the American Chemical Society. 
35-62 
English 
Methods for the synthesis of the biologically active dihydrodiol and diol epoxide metabolites of both carcinogenic and noncarcinogenic polycyclic aromatic hydrocarbons are reviewed. Four general synthetic routes to the trans-dihydrodiol precursors of the bay region anti and syn diol epoxide derivatives have been developed. Syntheses of the oxidized metabolites of several hydrocarbons via these methods are described. 
Harvey Ronald G.