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HERO ID
8220832
Reference Type
Journal Article
Title
Effect of leaves extract of indigenous species of Syzygium cumini on dental caries causing pathogens
Author(s)
Tahir, L; Ahmed, S; Hussain, N; Perveen, I; Rahman, S
Year
2012
Is Peer Reviewed?
0
Journal
International Journal of Pharma and Bio Sciences
ISSN:
0975-6299
Volume
3
Issue
3
Page Numbers
B1032-B1038
Language
English
Abstract
Dental caries is a common disease that results in tooth loss or cavitations. Medicines available in market though effectively treat dental caries but not without imparting the harmful effects. Medicinal plants have proven to be an effective and safe alternative to synthetic medicines. In vitro antibacterial activity of leaves of Syzygium cumini was studied against Streptococcus viridans, Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis. The aqueous, methanolic, hexane and ethyl acetate extract of leaves of S. cumini exhibited the antimicrobial activity against dental caries causing strains. The largest zone of inhibition was obtained with the methanolic extract against E. coli (20mm). Minimum Inhibitory Concentration (MIC) of extract was also determined against the selected microorganisms showing zone of inhibition ⥠8mm. The study concluded that the leaves of S. cumini possessed very good antibacterial activity against dental caries causing microorganisms and can be used as a potential source for making a phytomedicine that can be used to cure dental caries.
Keywords
Antibacterial; Dental caries; Ethyl acetate extract; Hexane; Methanol
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