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HERO ID
8224002
Reference Type
Journal Article
Title
Thin layer chromatography
Author(s)
Cai, L
Year
2014
Publisher
Blackwell Publishing Inc.
Volume
2014
Page Numbers
6.3.1-6.3.18
Language
English
DOI
10.1002/9780470089941.et0603s08
Abstract
Thin layer chromatography (TLC) is a quick, sensitive, and inexpensive technique used to determine the number of components in a mixture, verify the identity and purity of a compound, monitor the progress of a reaction, determine the solvent composition for preparative separations, and analyze the fractions obtained from column chromatography. This unit is mainly aimed at novice experimenters, describing in detail the strategies and principal steps for performing a TLC experiment, with illustrations of the relevant instruments, as well as approaches for obtaining and understanding results. Valuable practical tips and troubleshooting solutions are also provided throughout the unit. Curr. Protoc. Essential Lab. Tech. 8:6.3.1-6.3.18. © 2014 by John Wiley & Sons, Inc.
Keywords
Chromatography; Organic solvents; Separation; Silica gel; Staining; TLC
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