Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

8230109

Reference Type

Journal Article

Title

Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells

Author(s)

Kusaczuk, M; Krętowski, R; Naumowicz, M; Stypułkowska, A; Cechowska-Pasko, M; ,

Year

2018

Is Peer Reviewed?

Yes

Journal

International Journal of Nanomedicine
ISSN: 1176-9114
EISSN: 1178-2013

Publisher

DOVE MEDICAL PRESS LTD

Location

ALBANY

Page Numbers

2279-2294

Language

English

PMID

29695906

DOI

10.2147/IJN.S158393

Web of Science Id

WOS:000430007000001

URL

https://www.dovepress.com/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage--peer-reviewed-article-IJN
Exit

Abstract

Recently, the focus of oncological research has been on the optimization of therapeutic strategies targeted at malignant diseases. Nanomedicine utilizing silicon dioxide nanoparticles (SiNPs) is one such strategy and is rapidly developing as a promising tool for cancer diagnosis, imaging, and treatment. Nevertheless, little is known about the mechanisms of action of SiNPs in brain tumors.