Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
8230109
Reference Type
Journal Article
Title
Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells
Author(s)
Kusaczuk, M; Krętowski, R; Naumowicz, M; Stypułkowska, A; Cechowska-Pasko, M; ,
Year
2018
Is Peer Reviewed?
Yes
Journal
International Journal of Nanomedicine
ISSN:
1176-9114
EISSN:
1178-2013
Publisher
DOVE MEDICAL PRESS LTD
Location
ALBANY
Page Numbers
2279-2294
Language
English
PMID
29695906
DOI
10.2147/IJN.S158393
Web of Science Id
WOS:000430007000001
URL
https://www.dovepress.com/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage--peer-reviewed-article-IJN
Exit
Abstract
Recently, the focus of oncological research has been on the optimization of therapeutic strategies targeted at malignant diseases. Nanomedicine utilizing silicon dioxide nanoparticles (SiNPs) is one such strategy and is rapidly developing as a promising tool for cancer diagnosis, imaging, and treatment. Nevertheless, little is known about the mechanisms of action of SiNPs in brain tumors.
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity