US EPA

8245365 

Journal Article 

In vitro lipid peroxidation assay of Rumex vesicarius L 

Prasad, PSH; Ramakrishnan, N 

2012 

1 

International Journal of Pharmacy and Pharmaceutical Sciences
ISSN: 2656-0097
EISSN: 0975-1491 

4 

SUPPL.1 

368-370 

English 

The present investigation is aimed to carry out the invitro lipid peroxidation and total antioxidant capacity of Rumex vesicarius L. (Polygonaceae), Rumex vesicarius L. is commonly called as "Bladder dock" it is a wild green leafy vegetable cultivated in many parts of India and used in daily diet. Lipid peroxidation was monitored by the change in optical density of the prepared concentrations (1.5-1000μg/ml) and the inhibition percentage was calculated. FeSo 4induced peroxidation was inhibited by standard antioxidans Quercitin. The inhibition percentage of the plant extracts (hexane, chloroform, ethylacetate, ethanol and aqueous) increased with increase in concentrations. Of all the five extracts analyzed and compared the ethanol extract of the plant showed maximum inhibition percent of 62.24 at 1000μg/ml, followed by other extracts while the ethylacetate extract showed lowest inhibition percent of 34.27. The plant extracts inhibited Lipid peroxidation, thus it could slow down aging process and can improve immune responses. The present study indicates that Rumex vesicarius L can be a potential source of natural antioxidant. 

In-vitro lipid peroxidation; Rumex vesicarius L.; Total antioxidant capacity