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8253676 
Journal Article 
Bismuth-catalyzed direct substitution of the hydroxy group in alcohols with sulfonamides, carbamates, and carboxamides 
Qin, H; Yamagiwa, N; Matsunaga, S; Shibasaki, M 
2007 
Yes 
Angewandte Chemie (International Edition)
ISSN: 1433-7851
EISSN: 1521-3773 
46 
3 
409-413 
English 
(Figure Presented) No preactivation of the alcohol substrates is required in allylic, propargylic, and benzylic aminations catalyzed by a combination of commercially available Bi(OTf)3 and KPF6, mostly at room temperature (see scheme). The substitution reactions of readily accessible allylic, propargylic, and benzylic alcohols with sulfonamides, carbamates, and carboxamides give the desired amine products in up to 99% yield. © 2007 Wiley-VCH Verlag GmbH S. Co. KGaA. 
Animation; Bismuth; Homogeneous catalysis; Nucleophilic substitution; Synthetic methods