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HERO ID
8257423
Reference Type
Journal Article
Title
Calcium-catalyzed friedel-crafts alkylation at room temperature
Author(s)
Niggemann, M; Meel, MJ
Year
2010
Is Peer Reviewed?
Yes
Journal
Angewandte Chemie (International Edition)
ISSN:
1433-7851
EISSN:
1521-3773
Volume
49
Issue
21
Page Numbers
3684-3687
Language
English
DOI
10.1002/anie.200907227
Abstract
Chemical Equatation Representation A novel calcium catalyst was found to efficiently functionalize electron-rich arenes with secondary and tertiary benzylic, propargylic, and allylic alcohols under very mild reaction conditions. The new catalyst system significantly enlarges the scope of the reaction, which was previously limited except for the few examples with secondary benzylic alcohols. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.
Keywords
Alcohols; Allylic compounds; Arylation; Calcium; Friedel-crafts reaction
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