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8261151 
Journal Article 
The Different Kinds of Reaction involved in synthesis of 2-substituted Benzothiazole and its derivatives: A review 
Jaiswal, S; Mishra, AP; Srivastava, A 
2012 
0 
Research Journal of Pharmaceutical, Biological and Chemical Sciences
ISSN: 0975-8585 
3 
1 
631-641 
English 
Benzoheterocycles such as benzothiazoles can serve as unique and versatile scaffolds for experimental drug design. Among the all benzohaterocycles, benzothiazole has considerable place in research area especially in synthetic as well as in pharmaceutical chemistry because of its potent and significant pharmacological activities. The small and simple benzothiazole nucleus possesses numerous pharmacological activities like- antitumor, antimicrobial, anti-inflammatory, anticonvulsant, and antidiabetic activities. Since, a wide range of different reactions are available for synthesizing 2-substituted benzothiazole nucleus and its derivatives by using different type of catalysts but a real need exists for new procedures that support many kinds of structural diversity and various substitution. The present review focuses on the different kind of reactions involved in synthesis as well as cyclisation of benzothiazole nucleus and its derivatives. 
Benzothiazole derivatives; Benzothiazoles; Catalysts; Cyclization