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8302099 
Journal Article 
Topical immunomodulators for the treatment of external genital warts, cutaneous warts and molluscum contagiosum 
Hengge, UR; Cusini, M 
2003 
149 
66 
15-19 
English 
Topical immunomodulators (TIMs) include both immunostimulatory and immunosuppressive agents. Newer immunostimulatory compounds such as imidazoquinolines (e.g. imiquimod) act by cytokine secretion from monocytes/macrophages (interferon-α, interleukin-12, tumour-necrosis factor-α), leading to a Th1-dominance and cell-mediated immunity. This immune milieu has been clinically used to treat viral infections such as human papillomavirus (condyloma and common warts), herpes simplex virus and mollusca in immunocompetent and immunosuppressed patients. 
Human papillomavirus; Imiquimod; Molluscum contagiosum; Topical immunomodulators 
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