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8302759 
Journal Article 
Generalization of the Triptycene Concept. Use of Diaryne Equivalents in the Synthesis of Iptycenes 
Hart, H; Shamouilian, S; Takehira, Y 
1981 
Yes 
Journal of Organic Chemistry
ISSN: 0022-3263
EISSN: 1520-6904 
46 
22 
4427-4432 
English 
simple one-step synthesis of triptycene analogues prepared by reaction of a diaryne equivalent with anthracenes is described. For example, 1,2,4,5-tetrabromobenzene, anthracene, and n-butyllithium gave 5,7,12,14-tetrahydro- 5,14[l’,2']:7,12[ 1”,2”]-dibenzenopentacene (2, R = H.; trivially called a p-pentiptycene) in good yield. Other tetrabromoarenes were used to similarly prepare 2 (R = CH3), 2 (R = OCH3), and the naphtho analogue 13. Use of 9,10-dimethoxyanthracene gave the tetramethoxy bridgehead-substituted pentiptycene 11. 4,5-Dibromo- 3,6-diiodo-o-xylene functioned as an ortho diaryne equivalent to give the o-pentiptycene 3 (R = CH3). The synthesis of heptiptycene 4 (5,6,ll,12,17,18-hexahydro-5,18[l’,2']:6,ll[l”,2”]:12,17[l,”,2,”]-tribenzenotrinaphthylene has been improved, and the intermediate cycloalkyne 22 has been trapped with various dienes. © 1981, American Chemical Society. All rights reserved.