US EPA

8308009 

Journal Article 

Evaluation of wound healing activity of hexane and methanolic extract of fruit pulp of Momordica balsamina Linn in albino rats 

Ilango, K; Prakash Yoganandam, G; Usha, K; Priyanga, KS; Ilansezhiyan, M; Kalaiarasi, V 

2010 

1 

International Journal of Pharmacy and Pharmaceutical Sciences
ISSN: 2656-0097
EISSN: 0975-1491 

2 

1 

88-92 

English 

Wound healing is an important process which is the basis of various surgical manipulations. Restoration of damaged tissue, wound or facture is an important process which plays vital role in survival of life. Momordica balsamina Linn (Cucurbitaceae) is a monoecious, very slender, branched, grooved, sub glabrous tendrils. It has tremendous medicinal values such as leprosy, piles, jaundice etc., The present study was undertaken on hexane and methanolic extract of fruit pulp of M.balsamina on wound healing activity through oral and topical routes on excision wound model. The activity was compared with standard drug Ciprofloxacin (10 mg/kg) and Povidone iodine ointment (5% w/w) respectively. The hexane extract was found to have better wound healing effect than methanolic extract on both route of administration and the oral route of administration shows faster rate of healing when compared with topical application. 

Momordica balsamina; Oral and topical administration; Wound healing activity