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8308668 
Journal Article 
Antioxidant effects of ginseng powder on liver of benzo(α)pyrene- treated mice 
Kim, HJ; Bo, MH; Lee, JW; Im, HG; Lee, IS 
2007 
Chk 
Han'guk Sikp'um Kwahakhoe Chi
ISSN: 0367-6293 
39 
2 
217-221 
Korean 
In order to determine the effects of ginseng powder on the antioxidant enzyme activities of hepatotoxicity in binzo(α)pyrene[B(α)P]-treated mice, the mice were divided into 5 groups. Ginseng powder was injected intraperitoneally once a day for 5 siccessive daus. Fp;;pwed by the administration of B(α)P treatment on the fifth day. We also evaluated the relationship existing between lipid peroxidation and ginseng powder om pxodatove stress. The increased activities of superoxide dismutase, xatalase, and glutathione perpxodase pbserved following B(α)P-treatment were reduced as the result of gindeng powder treatment. Whereas, the glutathione content and glutathione S-transferase activity depleted by B(α)P were increased significantly, but the B(α)P-associated elevation of cytochrome P-450 activities and lipid peroxide content were reduced as the result of ginseng powder treatment. These results indicate that ginseng powder may exert a protective effect agains B(α)P-induced hepatotoxicity in mice. © The Korea Society of Food Science and Technology. 
Antioxidant activity; B(α)P; Ginseng powder; Hepatotoxicity