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8315613 
Journal Article 
Antioxidant, Anti-Inflammatory, Cytotoxicity and cytoprotection activities of crassocephalum crepidioides (Benth.) S. Moore. Extracts and its phytochemical composition 
Wijaya, S; Nee, TK; Jin, KT; Din, WM; Wiart, C 
2011 
67 
1 
157-165 
English 
The hexane, ethyl acetate, ethanol and water extracts of Crassocephalum crepidioides (Benth.) S. Moore. were assessed for their antioxidant, anti-inflammatory, cytoxicity and cytoprotective activities. The ethanol extract displayed profound antioxidant activities and inhibited the enzymatic activity of 5-lipoxygenase (5-LOX). The ethanol extract of Crassocephalum crepidioides (Benth.) S. Moore. at a concentration of 100 μg/ml, was non-toxic against MRC-5 and HepG2 cell lines. At the concentration of 25 μg/ml it gave a percentage of cytoprotection with the value of 69.47%. Phytochemical analysis of the ethanol extract revealed the presence of phenols and flavonoids with 422.22 gallic acid equivalent (mg/g) and 3.46 quercetin equivalent (mg/g). Phenolic compounds and flavonoids impart to Crassocephalum crepidioides (Benth.) S. Moore. its biological. properties. © EuroJournals Publishing, Inc. 2011. 
Anti-inflammatory; Antioxidant; Crassocephalum crepidioides; Cytoxicity and Cytoprotective