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8316235 
Journal Article 
Synthesis of functionalized 1-azabicyclo[3.1.0]hexanes: Studies towards ficellomycin and its analogs 
Chen, G; He, Z; Yudin, AK 
2014 
Yes 
Heterocycles
ISSN: 0385-5414 
Japan Institute of Heterocyclic Chemistry 
8 
2 
1299-1310 
English 
The molecule of antibiotic agent ficellomycin contains an intriguing array of functional groups assembled around a bicyclic aziridine core. To address the challenges of constructing ficellomycin derivatives, we have developed cycloamination methodology for the stereocontrolled transformation of unprotected aziridine-containing olefins. The present paper discusses application of this process towards synthesis of ficellomycin. © 2014 The Japan Institute of Heterocyclic Chemistry.