US EPA

8317569 

Journal Article 

Antioxidant and antibacterial activity of some leaves extracts (Methanol, ethyl acetate and N-Hexane) of scurrula fusca G.Don 

Sembiring, HB; Barus, T; Marpaung, L; Simanjuntak, P 

2015 

Sphinx Knowledge House 

8 

9 

24-30 

English 

The purpose of this research was to test antioxidant and antibacterial activity of some leaves extracts of Scurrula fusca G.Don. The antioxidant activity of methanol, ethyl acetate and n-hexane extracts of S. fusca tested by Free Radical Scavenging method using DPPH (1,1-diphenyl-2-picrylhydrazil) are considered very strong since their IC50 value were less than 50 µg/ml (32.96; 27.35 and 40.31 mg/ml respectively). Antibacterial activity test by Disc Difusion method for the extracts showed that methanol extract had activity with category susceptible at concentration of 550 mg/ml against Gram Positive bacteria (Streptococcus aureus and Bacillus cereus) with inhibition zone 17.80 and 18.26 mm respectively, and at the same concentration showed activity with category intermediate against Gram Negative bacteria (Pseudomonas aeruginosa and Escerichia coli). Ethyl acetate extract showed activity with category susceptible at concentration of 450 mg/ml against same Gram Positive bacteria (18.28 mm and 18.05 mm) and activity with category intermediate against Gram Negative bacteria. n-Hexane extract showed activity with category resistant (9.34 - 10.10 mm) against all bacteria tested at concentration of 550 mg/ml. © 2015, Sphinx Knowledge House. All right reserved. 

Antibacteria; Antioxidant; Scurrula fusca G.Don