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8325612 
Journal Article 
Evaluation of antimicrobial activity of leaf extracts Of Pimpinella tirupatiensis 
Ranjit, P; Giri, A; Deepak Raj, K 
2016 
0 
Research Journal of Pharmaceutical, Biological and Chemical Sciences
ISSN: 0975-8585 
Research Journal of Pharmaceutical, Biological and Chemical Sciences 
7 
4 
1220-1225 
English 
Pimpenella tirupatensis is an endemic medicinal plant of Andhra Pradesh and is known for its cardio protective, hepatoprotective, antihyperglycemic and antihyperlipidamic activity. The antimicrobial activity of different concentrations (50 to 150 μg/mL) of p.tirupatensis leaf extracts in various solvents (Acetone, methanol, ethyl acetate, chloroform, and hexane) was evaluated against pathogenic bacterial strains (Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhimurium, Proteus mirabilis, Bacillus subtilis, and Proteus vulgaris). Among all the extracts, tested leaf acetone extract displayed strong antimicrobial activity against Proteus mirabilis (inhibition zone diameter 16 mm). It also exhibited low values of both MIC and MBC. 
Antimicrobial activity; Inhibition zone diameter MIC; MBC; Pimpenella tirupatensis