Health & Environmental Research Online (HERO)


Print Feedback Export to File
8326543 
Journal Article 
The Reductive Alkylation of Primary Aromatic Amines with Raney Nickel and Alcohols 
Ainsworth, C 
1956 
Yes 
Journal of the American Chemical Society
ISSN: 0002-7863
EISSN: 1520-5126 
78 
8 
1635-1636 
English 
Secondary amines form readily from primary aromatic amines, primary or secondary alcohols and relatively large amounts of Raney nickel. Aniline, 2,5-dimethoxyaniline and 2-naphthylamine represent the amines successfully employed while ethyl, n- and isopropyl, n-butyl, cyclohexyl and benzyl alcohols represent the alcohols that were used. The reaction takes place at steam-bath temperature and yields of pure secondary amines are generally satisfactory. Benzylamine and 2-phenylethylamine with excess Raney nickel in ethyl alcohol gave dibenzylamine and di-(2-phenylethyl)-amine, respectively. © 1956, American Chemical Society. All rights reserved.