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HERO ID
8327131
Reference Type
Journal Article
Title
Effect of starvation on expression of troponin complex genes and ER stress associated genes in skeletal muscles
Author(s)
Kwon, K; Yoo, BK; Ko, Y; Choi, JY; Kwon, OY; Kim, SW
Year
2018
Is Peer Reviewed?
1
Journal
Biomedical Research
ISSN:
0970-938X
EISSN:
0976-1683
Volume
29
Issue
11
Page Numbers
2368-2372
Language
English
DOI
10.4066/biomedicalresearch.54-18-598
Abstract
Little is known about the mechanism of gene expression changes in skeletal muscle during starvation. This study investigated the influence of starvation on gene expression of troponin complex (TnC, TnI and TnT), tropomyosin (Tpm), and endoplasmic reticulum (ER) stress associated proteins (BiP, calreticulin, PDI, and ATF6) in three kinds of skeletal muscles of Gryllus bimaculatus. Dorsal ventral flight muscle (DVM), dorsal longitudinal, and dorsal wing flight muscles (DWM) were identified as typical skeletal muscles by H&E staining. Obvious gene expression was detected in the DVM, but not in the DLM or DWM. In addition to gene expression in DVM, gene expression of decorin, a type of myokine, was also significantly increased by starvation. This is the first study that reports the effect of starvation on expression of troponin complex genes and ER stress associated genes in three types of skeletal muscles. © 2018, Scientific Publishers of India. All rights reserved.
Keywords
Endoplasmic reticulum (ER) stress associated proteins (BiP,Calreticulin,PDI and ATF6); Gryllus bimaculatus; Starvation; Tropomyosin (Tpm); Troponin complex (TnC,TnI and TnT)
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