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8336566 
Journal Article 
Comparison between orthonasal and retronasal flavour perception at different concentrations 
Diaz, ME 
2004 
Yes 
Flavour and Fragrance Journal
ISSN: 0882-5734 
19 
6 
499-504 
English 
To be perceived, flavour molecules need to reach the olfactory epithelium, located in the nasal cavity. This can be achieved through orthonasal (sniff) or retronasal (mouth) airways. The intensity perceived will depend on the number of molecules that reach the receptor cells. The aim of this study is to compare the dose-response behaviour of flavour molecules, depending on whether the flavours were sniffed or tasted. Six flavour compounds were studied, including a homologous series of esters, and the differences on dose-response curves (intensity vs. concentration) correlated to the physicochemical characteristics of the flavour molecules. In addition, the matching concentration in water to get the same intensity by sniff as a reference tasted by mouth for some flavour compounds was determined. It was shown that the differences in orthonasal and retronasal perception depend strongly on the physical characteristics of the aroma chemicals. Copyright © 2004 John Wiley & Sons, Ltd. 
Dose-response; Flavour perception; Flavour release; Orthonasal; Retronasal