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HERO ID
8345543
Reference Type
Journal Article
Title
Hypolipidemic effect of fenugreek: A clinical study
Author(s)
Prasanna, M
Year
2000
Is Peer Reviewed?
Yes
Journal
Indian Journal of Pharmacology
ISSN:
0253-7613
EISSN:
19983751
Volume
32
Issue
1
Page Numbers
34-36
Language
English
Abstract
Objective: To investigate the hypolipidemic effect of fenugreek in hypercholesterolaemic patients. Methods: Fenugreek (Trigonella foenum graecum) seeds (FG) were powdered and extracted with hexane to remove its lipid content and alcohol to remove the saponins. This powder was used for the study. The patients were divided into 3 groups of 6 each as follows: Group I received placebo 50 gm (rice powder and Bengal gram powder in equal measures); Group II -placebo 25 gm + FG 25 gm and Group III -FG 50 gm. Patients were directed to take each 50 gm pack orally before lunch and dinner every day for 20 days. Blood samples were collected after overnight fasting on 0, 10th and 20th days during test period and estimated for lipid profile. Results: There were no significant changes in lipid profile of group I patients. In groups II and III serum cholesterol, triglycerides and VLDL levels were significantly decreased when compared to group I. Conclusion: FG powder given orally before food at 25 and 50 gm twice a day may have hypolipidemic effect in hypercholesterolaemic patients.
Keywords
Fenugreek; Hypolipidemic effect
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