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HERO ID
8358217
Reference Type
Journal Article
Title
Solid phase synthesis of aryl ethers via the mitsunobu reaction
Author(s)
Rano, TA; Chapman, KT
Year
1995
Is Peer Reviewed?
1
Journal
Tetrahedron Letters
ISSN:
0040-4039
EISSN:
1873-3581
Volume
36
Issue
22
Page Numbers
3789-3792
Language
English
DOI
10.1016/0040-4039(95)00607-E
Abstract
A procedure for the preparation of aryl ethers on a solid support employing the Mitsunobu reaction is described. Either polymer bound phenols or benzyl alcohols react rapidly and cleanly with TMAD/Bu3P and the appropriate electrophile/nucleophile to provide the aryl ether in excellent yield and purity after cleavage from the solid support. © 1995.
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