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Journal Article 
Fatty acid profile and bio-efficacy of wheat germ oil in hyperlipidemic rabbits 
Rehman, HU; Farooq, U; Akram, K; Hayat, Z; Shafi, A; Sarfarz, F; Sidhu, A; Hakim, A 
Pakistan Journal of Agricultural Sciences
ISSN: 0552-9034 
University of Agriculture 
Wheat germ oil (WGO) is highly nutritious with significant biological value. In current research work, WGO was extracted through solvent extraction method by using hexane as solvent. The oil was analyzed for fatty acid profile and was later used for biological study in order to investigate hypocholesterolemia potential by using rabbits as animal model. The results revealed that the WGO contained 82.64 % unsaturated fatty acids with linoleic acid (82.64) as leading fatty acid and linolenic acid (6.81%). Other major fatty acid in the oil was oleic acid (16.12%). The biological studies showed that there was significant improvement in lipid profile of hyperlipidemic rabbits when fed with WGO as evident from reduction in cholesterol, triglycerides, LDL and VLDL whereas an increase in HDL level. It was concluded that the WGO possessed significant hypocholesterolemia potential. © 2021, University of Agriculture. All rights reserved. 
Biological study; Hyperlipidemic rabbits; WGO; Wheat germ oil