Health & Environmental Research Online (HERO)


Print Feedback Export to File
8363431 
Journal Article 
CATALYTIC AMIDE FORMATION OF N-STEAROYL LYSINE FROM CARBOXYLIC ACID IN MIX SOLVENT: ANALYSIS OF THE RESPONSE SURFACE 
Masyithah, Z; Hutagalung, A; Alfizah, D; Kristin Sinaga, E; Ginting, A 
2021 
Asian Research Publishing Network 
16 
1 
37-44 
English 
N-stearoyl lysine is a non-ionic surfactant. N-stearoyl lysine was synthesized by reacting stearic acid (SA) and lysine (L). In the synthesis of N-stearoyl lysine, the interaction effect between the substrate ratio, solvent ratio, and catalyst concentration was observed to obtain the optimal percentage of stearic acid conversion. The catalytic oxidation process is carried out by reacting lysine with stearic acid at a substrate ratio of 2–4 (L/SA), with the addition of mixed solvent hexane and 2-propanol with a ratio of 1–3 (v/wSA) and calcium oxide catalyst at 3-7%. (w/wSA). The reaction was carried out at a temperature of 65 °C and a time of 3 hours. The optimal conditions using the response surface analysis were obtained at a substrate ratio of 4 (L/SA), a solvent ratio of 3 (v/wSA), and a catalyst concentration of 5%, and the resulting conversion of stearic acid was 85.2%. © 2021, ARPN Journal of Engineering and Applied Sciences. All rights reserved. 
calcium oxide; lysine; mix-solvent; response surface analysis; stearic acid