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8364745 
Journal Article 
SnCl2 catalyzed direct synthesis of pyrroles under aqueous conditions 
Tejeswararao, D; Srikanth, B 
2020 
Yes 
Asian Journal of Chemistry
ISSN: 0970-7077
EISSN: 0975-427X 
Asian Publication Corporation 
32 
4 
795-802 
English 
Synthetic substituted pyrroles are related with interesting biological activities, yet they remain inadequately explored within drug discovery. Late years have seen a growing interest in synthetic approaches that can provide access to structurally novel pyrroles so that the biological usefulness of this compound class can be more fully investigated. Herein, an efficient and versatile practical protocol for the pyrroles using stannous(II) chloride dihydrate as catalyst is described under aqueous conditions at 55 ºC in high yields. Also, this method is applicable for the preparation of diversity and oriented pyrrole derivatives. © 2020 Chemical Publishing Co.. All rights reserved. 
5-dione; Aqueous medium; Diversity synthesis; Hexane-2; Pyrrole; Stannous(II) chloride