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8386361 
Journal Article 
GC determination of related substances of benzyl alcohol injection 
Zhang, C; Xu, AX; Wang, HL; Feng, L 
2016 
Chk 
Yaowu Shengwu Jishu
ISSN: 1005-8915 
China Pharmaceutical University 
23 
3 
241-244 
Chinese 
To establish a GC method for determination of the content of Benzyl alcohol injection, using Phenomenex ZB-WAX (30 m×0.32 mm×0.5 μm) capillary column, programmed temperature(the initial temperature is 50℃ and maintain this temperature for 15 minutes, then the temperature increased to 220℃ at rate of 5℃ /min, maintain this temperature for 35 minutes); nitrogen as carrier gas; the temperature of injection port is 200℃; the temperature of FID detection is 310℃.Results showed that the GC method for the determination of the content of Benzyl alcohol injection was good in determining related substances and the main components can be completely separated and the limit of detection is 1.4 ng. This method is easy to operate, accurate, reliable, and the related substances have good separating degree, so the method can be used to control the quality of Benzyl alcohol injection. © 2016, Editorial Board of Pharmaceutical Biotechnology. All right reserved. 
Benzaldehyde; Benzoic acid; Benzyl alcohol injection; Benzyl ether; GC; Related substance