Tafur, S; Jones, WE; Dorman, DE; Logsdon, EE; Svoboda, GH
In a continuing effort to study thoroughly the alkaloids of Catharanthus roseus, new dimeric alkaloids were isolated and characterized. Structures are proposed for leurocolombine and vinamidine based on UV, IR, PMR, highâresolution mass spectrometry, and CMR. Pseudovincaleukoblastine diol was identified by PMR and mass spectrometry. Leurocolombine exhibited antimitotic activity and marginal antitumor activity against the Ridgeway osteogenic sarcoma. Copyright © 1975 WileyâLiss, Inc., A Wiley Company
Alkaloidsâisolation of three from Catharanthus roseus, characterization by UV, IR, NMR, and mass spectra; Catharanthus roseusâisolation of three dimeric alkaloids, characterization by UV, IR, NMR, and mass spectra; Leurocolombineâisolation from Catharanthus roseus, UV, IR, NMR, and mass spectral structure identification; Pseudovincaleukoblastine diolâisolation from Catharanthus roseus, UV, IR, NMR, and mass spectral structure identification; Vinamidineâisolation from Catharanthus roseus, UV, IR, NMR, and mass spectral structure identification; Vinca roseaâisolation of three dimeric alkaloids, characterization by UV, IR, NMR, and mass spectra