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HERO ID
8398065
Reference Type
Journal Article
Title
Stability of cyclophosphamide containing infusions
Author(s)
Mittner, A; Vincze, Z; Jemnitz, K
Year
1999
Is Peer Reviewed?
Yes
Journal
Die Pharmazie
ISSN:
0031-7144
Volume
54
Issue
3
Page Numbers
224-225
Language
English
Abstract
The stability of cyclophosphamide containing Normal Saline admixture solution for infusion at various temperatures has been studied. The difference in stability during storage at room temperature and at 2-8 °C was observed based on an HPLC assay. Stored in a refrigerator, the decomposition of the active agent was less than 1% on the seventh day, and remained under 1.11% on the 14th day. Under room temperature the decomposition exceeded 10% on the seventh day and was over 25% on the 14th day.
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