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HERO ID
8398843
Reference Type
Journal Article
Title
A well-defined complex for palladium-catalyzed aerobic oxidation of alcohols: Design, synthesis, and mechanistic considerations
Author(s)
Jensen, DR; Schultz, MJ; Mueller, JA; Sigman, MS
Year
2003
Is Peer Reviewed?
Yes
Journal
Angewandte Chemie (International Edition)
ISSN:
1433-7851
EISSN:
1521-3773
Volume
42
Issue
32
Page Numbers
3810-3813
Language
English
DOI
10.1002/anie.200351997
Abstract
A breath of fresh air: A variety of alcohols are oxidized using 0.5-0.1 mol% of the catalyst, and in some cases the oxidation can simply be carried out open to the air (see scheme). Mechanistic insight into the mechanism is provided by a crystal structure that shows remarkable hydrogen bonds between the coordinated water and acetate ligands and an unprecedented large kinetic isotope effect.
Keywords
Alcohols; Oxidation; Oxygen; Palladium; Reaction mechanisms
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