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8406810 
Journal Article 
Homogeneous biocatalysis in both fluorous biphasic and supercritical carbon dioxide systems 
Hobbs, HR; Kirke, HM; Poliakoff, M; Thomas, NR 
2007 
Yes 
Angewandte Chemie (International Edition)
ISSN: 1433-7851
EISSN: 1521-3773 
46 
41 
7860-7863 
English 
(Figure Presented) HIP to be green: Cytochrome c and α-chymotrypsin (CMT) can be solubilized in either fluorous solvents or supercritical CO 2 by hydrophobic ion pairing (HIP) with perfluorinated anionic surfactants (Krytox 157 FSL, KDP 4606). A model system for homogeneous fluorous biphasic biocatalysis involving the CMT-KDP complex in hexane/ perfluoromethylcyclohexane is reported that simplifies both product separation and recycling of the biocatalyst. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA. 
Biocatalysis; Biphasic catalysis; Enzymes; Ion pairs; Supercritical fluids