Hepatoprotective activity of aerial parts of Plumbago zeylanica linn against carbon tetrachloride-induced hepatotoxicity in rats | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

8409314

Reference Type

Journal Article

Title

Hepatoprotective activity of aerial parts of Plumbago zeylanica linn against carbon tetrachloride-induced hepatotoxicity in rats

Author(s)

Kumar, R; Kumar, S; Patra, A; Jayalakshmi, S

Year

2009

Is Peer Reviewed?

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
ISSN: 2656-0097
EISSN: 0975-1491

Volume

Issue

SUPPL. 1

Page Numbers

171-175

Language

English

Abstract

The present study was conducted to evaluate the hepatoprotective activity of methanolic extract of aerial parts of Plumbago zeylanica in CCl 4-induced hepatotoxicity in wistar rats. Silymarin (100mg/kg, p.o.) was given as reference drug. The extract of aerial parts of Plumbago zeylanica have shown very significant hepatoprotection against CCl4-induced hepatotoxicity in wistar rats by reducing serum total bilirubin, SGPT ,SGOT and ALP levels. Histopathological studies also confirmed the hepatoprotective nature of the extract.

Keywords

Biochemical parameter; Flavonoids; Histopathological studies; Triterpenes