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8415244 
Journal Article 
Antibacterial activities of Et-OH extract from extruded white ginseng on tooth decay bacteria 
Son, HJ; Han, MS; Ryu, GH 
2009 
38 
7 
951-957 
Korean 
In this study, antibacterial activity of extruded ginseng extract by 60 and 80% Et-OH were investigated by agar diffusion assay against two bacteria causing dental caries (Streptococcus mutans and Lactobacillus casei). Extrusion conditions were 20% moisture content 100°C and 140°C barrel temperature. The inhibition effect of 60% Et-OH ginseng extract was higher than 80% Et-OH ginseng extract. The minimum inhibitory concentration (MIC) of 80% Et-OH extruded ginseng extract at 140 and 100°C barrel temperature against L.casei were 100 and 150 mg/mL respectively using broth assay method. The amount of glucosyltransferase (GTase) inhibitory content was the highest in extruded ginseng at 140°C barrel temperature with 60% Et-OH. Moreover, n-hexane and n-butanol fraction ginseng extract had potential against tested bacteria. Our results demonstrated that antibacterial activities of extruded ginseng extract at 140°C barrel temperature were more effective than Ex-100°C, RG and WG. 
Antibacterial activity; Ethanol extract; Extrusion condition; Ginseng