Antioxidant and hepatoprotective activities of Ocimum basilicum Linn. and Trigonella foenum-graecum Linn. against H2O2 and CCL4 induced hepatotoxicity in goat liver | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

841542

Reference Type

Journal Article

Title

Antioxidant and hepatoprotective activities of Ocimum basilicum Linn. and Trigonella foenum-graecum Linn. against H2O2 and CCL4 induced hepatotoxicity in goat liver

Author(s)

Meera, R; Devi, P; Kameswari, B; Madhumitha, B; Merlin, NJ

Year

2009

Is Peer Reviewed?

Yes

Journal

Indian Journal of Experimental Biology
ISSN: 0019-5189
EISSN: 0975-1009

Volume

Issue

Page Numbers

584-590

Language

English

PMID

19761043

Web of Science Id

WOS:000267790500008

Abstract

Significant hepatoprotective effects were obtained by ethanolic extract of leaves of O. basilicum and T. foenum-graecum against liver damage induced by H2O2 and CCl4 as evidenced by decreased levels of antioxidant enzymes (enzymatic and non enzymatic). The extract also showed significant anti lipid peroxidation effects in vitro, besides exhibiting significant activity in superoxide radical and nitric oxide radical scavenging, indicating their potent antioxidant effects.

Keywords

Hepatoprotection; Lipid peroxidation; Nitric oxide scavenging; Ocimum basilicum; Superoxide scavenging; Trigonella foenum-graecum