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8435895 
Journal Article 
Optimization of ultrasound-assisted extraction (UAE) process for the recovery of bioactive compounds from bitter gourd using response surface methodology (RSM) 
Chakraborty, S; Uppaluri, R; Das, C 
2020 
Yes 
Food and bioproducts processing
ISSN: 0960-3085
EISSN: 1744-3571 
Institution of Chemical Engineers 
AMSTERDAM 
120 
114-122 
English 
WOS:000519292300012 
This article presents the ultrasound-assisted extraction (UAE) of antioxidants, total phenolics and soluble proteins from bitter gourd (Momordica charantia). For comparative purposes, two sonication modes, namely normal and pulsed mode have been considered and the response variables have been addressed as a function of temperature, extraction time and vegetable to water ratio using response surface methodology (RSM) based design of experiments. Except for a few cases, the carried out investigations affirmed non-linear dependence of response variables (bioactive compound content) on control variables. Among all cases, pulsed mode sonication performed effectively than normal sonication mode with marginally lower vegetable to solvent ratio but higher bio-active content. These research findings indicate promising opportunities for pulsed mode ultra-sonication process with respect to conventional extraction methods for the production of bitter gourd aqueous extract for medicinal and functional food applications. © 2020 Institution of Chemical Engineers 
Bioactive compounds; Bitter gourd; Normal mode and pulsed mode; RSM; Solvent; Ultrasound-assisted extraction (UAE)