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Citation
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HERO ID
8436651
Reference Type
Journal Article
Title
Resolution of Racemates by Distillation with Inclusion Compounds
Author(s)
Kaupp, G
Year
1994
Is Peer Reviewed?
0
Journal
Angewandte Chemie: International Edition in English
ISSN:
0570-0833
Volume
33
Issue
7
Page Numbers
728-729
Language
English
DOI
10.1002/anie.199407281
Abstract
Will optical resolution by HPLC with chiral columns become obsolete? With a new technique, which should be amenable to upscaling, suspensions of crystalline host compounds such as 1 and 2 in hexane or water form 1:1 complexes with the one enantiomer of a racemic alcohol or ether such as 3 and 4 that fits best into its lattice. The two enantiomers can then be separated by vacuum distillation. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany
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