Zhao, QQ; Fu, HZ; Lin, KP; Zhou, ZQ; Wang, LX; Chen, LN; Luo, YH
Objective: To study the n-butanol-soluble chemical constituents of Xianzhuli. Methods: The chemical constituents were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their chemical structures were elucidated on the basis of physical and chemical properties and spectral data. Results: Sixteen compounds were isolated and identified as schaliside 1 (1), (Z)-4-hydroxycinnamyl alcohol 4-O-β-D-glucopyranoside (2), β-hydroxypropiovanillone-3-O-β-D-glucopyranoside (3), dihydro-p-coumaryl alcohol γ-O-glucoside (4), (+)-lyonirenisol-3α-O-β-D-glucopyranoside (5), tortoside B (6), syringaresinol 4-O-β-D-glucoside (7), 5,5'-dimethoxylariciresinol 4'-O-β-D-glucopyranoside (8), 2,4,6-trimethoxyphenol-1-O-β-D- glucopyranoside (9), benzylalcohol-β-D-glucopyranoside (10), (1'R)-1'-(4-hydroxy-3,5-dimethoxylphenyl) propan-1'-ol-4-O- β-D-glucopyranoside (11), erythro-2,3-bis(4-hydroxy-3-methoxyphenyl)-3-butoxypropan1-1-ol (12), threo-2,3-bis(4-hydroxy-3- methoxyphenyl)-3-butoxypropan1-1-ol (13), syringarenol (14), lirioresinol-A (15), and (E)-p-coumaryl alcohol γ-O-methyl ether (16). Conclusion: Compounds 2-4, 6, 10-13, 15-16 are isolated from Xianzhuli for the first time. And the carbon spectrum data of compound 4 was supplemented. © 2021, Editorial Office of Chinese Traditional and Herbal Drugs. All right reserved.