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8467288 
Journal Article 
Drug-excipient interactions 
Crowley, P; Martini, L 
2001 
13 
3 
26-28+30 
English 
Although considered pharmacologically inert, excipients can initiate, propagate or participate in chemical or physical interactions with drug compounds, which may compromise the effectiveness of a medication. Excipients may also contain impurities or form degradation products that in turn cause decomposition of drug substances. This article explores some of these interactions and reactions, and calls for a better understanding of excipients properties.