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8516635 
Journal Article 
Rückstandsanalyse von Chlorkohlenwasserstoffen in Humanknochenmark durch hochauflösende Gas-Chromatographie mit Elektroneneinfang-Detektor 
Dmochewitz, S; Ballschmiter, K 
1982 
0 
Fresenius' Zeitschrift für Analytische Chemie
ISSN: 0016-1152 
Springer-Verlag 
310 
1-2 
6-12 
German 
In human bone marrow, a tissue with a high content of fat, the following organochlorine copounds were identified: α-, β- and γ-hexachlorocyclohexane (HCH/BHC), hexachlorobenzene (HCB), 4,4′-DDT, 4,4′-DDE, a complex pattern of polychlorinated biphenyls (PCB) and traces of dieldrin and heptachloroepoxide. The chlorinated hydrocarbons, as well as the lipids, were extracted with a mixture of n-hexane, acetone and methanol in a column technique. Adsorption chromatography on Florisil was employed to remove lipids from the extract. By eluting with n-hexane and n-hexane/diethyl ether (95/5 vol%) group separation of the chlorinated hydrocarbons was achieved. The identification and quantification of the single compounds was performed using high-resolution glass-capillary gas chromatography with electron capture detection. The quantitative basis was the extracted residue of lipids. The following mean concentrations (in μg/g of extractable lipid content) were found: α-HCH: 0.02; β-HCH: 1.3; γ-HCH: 0.01; HCB: 2.6; 4,4′-DDT: 0.4; 4,4′-DDE: 8.4; sum of PCB (60% chlorine): 6.4. The values correspond to those found for human adipose tissue. © 1982 Springer-Verlag.