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8533049 
Journal Article 
Potentially reversible acute cerebellar toxicity associated with Minnelide 
Khanipour Roshan, S; Spano, AD; Mckinney, AM; Nascene, DR; , 
2017 
1 
Neuroradiology
ISSN: 0028-3940
EISSN: 1432-1920 
Springer Verlag 
59 
4 
419-421 
English 
28303374 
Minnelide is an experimental antineoplastic agent that is currently the subject of a phase 1 clinical trial for the treatment of pancreatic and gastrointestinal malignancies. In this study, we documented two cases of reversible acute cerebellar toxicity (REACT) associated with Minnelide and compared its radiological manifestations with other cerebellotoxic agents. 
Cerebellar cortex; Cerebellar toxicity; Diffusion weighted imaging; Minnelide; Reversible acute cerebellar toxicity