Health & Environmental Research Online (HERO)


Print Feedback Export to File
8536700 
Journal Article 
Perbandingan aktiviti antioksidan halia (Zingiber officinale Roscoe) Malaysia dengan produk semula jadi terpilih dan kesannya terhadap kebolehidupan sel mioblas dalam kultur 
Sahardi, NFNM; Jaafar, F; Zakaria, SNA; Tan, JK; Nordin, MFM; Makpol, S 
2021 
0 
Sains Malaysiana
ISSN: 0126-6039 
Penerbit Universiti Kebangsaan Malaysia 
50 
5 
1445-1456 
English 
Ginger has been proven to possess various therapeutic effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant effects. However, data on the comparison of ginger antioxidant activity with that of other natural products are still lacking. This study aimed to analyse and compare the antioxidant properties of two types of Malaysian ginger extracts (GE1 and GE2) with that of selected natural products. The antioxidant activities were measured by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and ferric reducing antioxidant power (FRAP) assays, while cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfonyl)-2H-tetrazolium (MTS) assay. The order of the DPPH scavenging activities was as follows: vitamin C > palm tocotrienol-rich fraction (TRF) > α-tocopherol > N-acetylcysteine (NAC) > Ficus deltoidea > butylated hydroxytoluene (BHT) > Centella asiatica > GE2 > GE1 > Moringa oleifera > Kelulut honey; the order of the mean FRAP value was as follows: NAC > α-tocopherol > BHT > TRF > Ficus deltoidea > Moringa oleifera > GE2 = GE1 > Centella asiatica > Kelulut honey. The viability assays showed that both ginger extracts significantly increased the percentage of viable cells (p < 0.05). In conclusion, neither of the ginger extracts was cytotoxic toward cells and both possessed comparable antioxidant properties, indicating their potential for ameliorating oxidative stress. © 2021 Penerbit Universiti Kebangsaan Malaysia. All rights reserved. 
Antioxidant property; Gingerol; Malaysian ginger; Myoblasts; Shogaol