Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
854683
Reference Type
Journal Article
Title
Synthesis of functionalized SBA-15 with ordered large pore size and its adsorption properties of BSA
Author(s)
Nguyen, TPB; Lee, JW; Shim, WG; Moon, H
Year
2008
Is Peer Reviewed?
1
Journal
Microporous and Mesoporous Materials
ISSN:
1387-1811
Volume
110
Issue
2-3
Page Numbers
560-569
DOI
10.1016/j.micromeso.2007.06.054
Web of Science Id
WOS:000254689200043
URL
http://linkinghub.elsevier.com/retrieve/pii/S1387181107004076
Exit
Abstract
SBA-15, mesoporous material, is a very excellent candidate for drug delivery system because its pore size is easy to control according to synthesis conditions and the presence of swelling agent. In this study, a known swelling agent, 1,3,5-trimethylbenzene (TMB), was used to increase the pore size with increased aging temperature and prolonged aging time. Furthermore, 3-aminopropyltriethoxysilane (APTES) was incorporated on SBA-15 surface via post synthesis method to separate protein effectively. The samples were characterized by X-ray diffraction (XRD), nitrogen adsorption and desorption analyses, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier Transform Infrared (FT-IR). Adsorption capacity increased with temperature at the isoelectric point (pI) of bovine serum albumin (BSA) regardless of the pore size of SBA-15 samples. Release studies were carried out in the range of pH from neutral to basic solution on unmodified and amine-modified samples. In addition, the adsorption mechanism was investigated by employing the pseudo-first order, pseudo-second order, and intraparticle diffusion models. (C) 2007 Elsevier Inc. All rights reserved.
Keywords
functionalized SBA-15; bovine serum albumin; adsorption; release
Tags
IRIS
•
Trimethylbenzenes (Interagency Science Discussion Draft)
Primary Literature Search
Primary Literature Search- Exclusion
Excluded by Journal
Chemistry or Physical or Engineering
•
Trimethylbenzenes (TMB)
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity