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857136 
Journal Article 
Aminoketone, oxazole and thiazole synthesis. Part 15. 2- 4-(4-Halobenzenesulphonyl)-phenyl -5-aryloxazoles 
Schiketanz, I; Draghici, C; Saramet, I; Balaban, AT 
2002 
2002 
2 
64-72 
English 
WOS:000179583600007 
Acylaminoacylation of aromatic hydrocarbons (benzene, toluene, meta-xylene, mesitylene) with 2-[4-benzenesulfonyl-(4-halophenyl)]-5-oxazolones in the presence of anhydrous aluminum chloride leads to 2-aza-1,4-diones 5 which cyclize under the action of phosphorus oxychloride yielding the corresponding 2-[4-(4-halobenzenesulphonyl)-phenyl]-5-aryloxazoles 6. The para-halogens are chloro or bromo atoms. Electronic absorption, vibrational, H-1-NMR and C-13-NMR spectral data are presented. The UV and NMR spectra provide evidence for the non-coplanarity of the oxazole and mesityl rings. 
amoinoketone; oxazole; thiazole; acylaminoacylation; synthesis