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8572575 
Journal Article 
Synthesis, characterization and biological activity of some new 1,2,4-triazine derivatives 
Salimon, J; Salih, N 
2010 
2 
2 
1041-1045 
English 
The title compound 2-(4-(anthracen-9(10H)-ylideneamino)-4-(1,6-dihydro-1,2,4-triazin-5(2 H)-one)pyridine 6, molecular formula C29H43N5O, was obtained through a multi steps reactions using tricyclic ketone, anthrone, as starting material. All the newly synthesized compounds were characterized using spectroscopic methods such as FTIR, 1HNMR, 13CNMR and elemental analysis. All synthesized compounds were primary in vitro screened for their antibacterial activity against Gram-positive (Staphylococcus aureus ATCC 6538p, Staphylococcus epidermidis ATCC 12228 and Bacillus subtilis PTCC 1023) and Gram-negative (Escherichia coil ATCC 8739, Klebsiella pneumoniae ATCC 10031, and Pseudomonas aeruginosa ATCC 9027) bacteria by the drug diffusion method. 
1,2,4-triazine; Biological activity; Carbohydrazides; Spectral studies; Synthesis