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HERO ID
8586045
Reference Type
Journal Article
Title
Synthesis of 2,6-diazido-1-(N-substituted phenyl)-1,4-dihydropyridine- 3,5- dicarbaldehydes and their transformation into multivariant functionalities
Author(s)
Rajput, AP; Girase, PD
Year
2012
Is Peer Reviewed?
0
Journal
International Journal of ChemTech Research
ISSN:
0974-4290
Volume
4
Issue
2
Page Numbers
634-639
Language
English
Abstract
A series of new 2,7-diamino-9-(N-substituted phenyl)-9,10-dihydro-1,8,9-triaza-anthracene-3,6- dicarbonitriles 6a-d were prepared by condensation of malononitrile with 2,6-diamino derivatives 5a-d which have been prepared by the action of sodium dithionite on 2,6-diazido-1-(N-substituted phenyl)-1,4-dihydropyridine-3,5- dicarbaldehydes 4a-d which in turn were prepared by the treatment of sodium azide with 3a-d. The structures of the newly synthesized compounds have been confirmed on the basis of elemental analysis and spectral studies. The newly synthesized title compounds have been screened for their in vitro antimicrobial activities. Some of the compounds exhibited encouraging results.
Keywords
Antimicrobial activity; Azides; Dicarbonitriles; Dihdropyridines
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