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8586475 
Journal Article 
Synthesis of some new antimicrobial 5,6,7,8- tetrahydropyrimido[4,5-b]quinolone derivatives 
El-Hashash, MA; Sherif, SM; Badawy, AAE; Rashdan, HRM 
2014 
Scholars Research Library 
6 
4 
23-29 
English 
2-Amino-1-aryl-1,4,5,6,7,8-hexahydro-4-phenylquinoline-3-carbonitrile derivatives were synthesized by the reaction of cyclohexanone (1) with 2-benzylidinemalononitrile (2) and the appropriate of aniline derivatives. The reactivity of some of these newly synthesized derivatives toward carbon disulfide and further toward hydrazonoyl halides were also studied. In addition, the antimicrobial activity of the newly synthesized derivatives was reported. 
Antimicrobial activity; Hydrazonoyl halides; Pyrimidoquinolines; Tetrahydroquinoline